Anticoagulant, fibrinogenolytic and anti-platelet aggregation activities of Lablab purpureus (L.) Sweet seed radicle aqueous extract

The current study explores the anticoagulant, fibrinogenolytic and anti-platelet aggregation activities of Lablab purpureus (L.) Sweet seed radicle extract (LPRE). It is firstly reported that LPRE has protein at a concentration 1.5 mg/ml further evaluated for in gel electrophoresis. proteolytic activity was using casein gelatin as substrate. showed specific 0.35 U. increased plasma clotting time significantly showing its anticoagulant property. hydrolyzed A?, B? ? chains fibrinogen. Furthermore, inhibited platelet induced by agonist adenosine diphosphate (ADP).